Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats

Parathyroid hormone (PTH) is an effective bone anabolic agent, but it must be administered parenterally. An orally active anabolic agent would provide a valuable alternative for treating osteoporosis. NPS 2143 is a novel, selective antagonist (a “calcilytic”) of the parathyroid cell Ca(2+) receptor....

Descripció completa

Dades bibliogràfiques

Publicat a:	J Clin Invest
Autors principals:	Gowen, Maxine, Stroup, George B., Dodds, Robert A., James, Ian E., Votta, Bart J., Smith, Brian R., Bhatnagar, Pradip K., Lago, Amparo M., Callahan, James F., DelMar, Eric G., Miller, Michael A., Nemeth, Edward F., Fox, John
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Clinical Investigation 2000
Matèries:	Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC300853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10841518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI9038
Etiquetes:	Afegir etiqueta Sense etiquetes, Sigues el primer a etiquetar aquest registre!