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Getting to the Core of Repeat Expansions by Cell Reprogramming
In this issue of Cell Stem Cell, Ku et al. (2010) demonstrate that iPSCS derived from Friedreich’s ataxia patients exhibit expansion of the causative (GAA)(n) repeat, consistent with the repeat instability observed during intergenerational transmissions in humans. Furthermore, the epigenetic signatu...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3008408/ https://ncbi.nlm.nih.gov/pubmed/21040891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2010.10.005 |
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