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Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches

Cholesterol is an important lipid of mammalian cells. Its unique physicochemical properties modulate membrane behavior and it serves as the precursor for steroid hormones, oxysterols and vitamin D. Cholesterol is effluxed from the late endosomes/lysosomes via the concerted action of at least two dis...

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Detalhes bibliográficos
Main Authors: Rosenbaum, Anton I., Maxfield, Frederick R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008286/
https://ncbi.nlm.nih.gov/pubmed/20807315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06976.x
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