A traditional herbal medicine enhances bilirubin clearance by activating the nuclear receptor CAR

Yin Zhi Huang, a decoction of Yin Chin (Artemisia capillaris) and three other herbs, is widely used in Asia to prevent and treat neonatal jaundice. We recently identified the constitutive androstane receptor (CAR, NR1I3) as a key regulator of bilirubin clearance in the liver. Here we show that treat...

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Bibliographic Details
Main Authors: Huang, Wendong, Zhang, Jun, Moore, David D.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2004
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC300765/
https://ncbi.nlm.nih.gov/pubmed/14702117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200418385
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