Systemic combinatorial peptide selection yields a non-canonical iron-mimicry mechanism for targeting tumors in a mouse model of human glioblastoma

The management of CNS tumors is limited by the blood-brain barrier (BBB), a vascular interface that restricts the passage of most molecules from the blood into the brain. Here we show that phage particles targeted with certain ligand motifs selected in vivo from a combinatorial peptide library can c...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Staquicini, Fernanda I., Ozawa, Michael G., Moya, Catherine A., Driessen, Wouter H.P., Barbu, E. Magda, Nishimori, Hiroyuki, Soghomonyan, Suren, Flores, Leo G., Liang, Xiaowen, Paolillo, Vincenzo, Alauddin, Mian M., Basilion, James P., Furnari, Frank B., Bogler, Oliver, Lang, Frederick F., Aldape, Kenneth D., Fuller, Gregory N., Höök, Magnus, Gelovani, Juri G., Sidman, Richard L., Cavenee, Webster K., Pasqualini, Renata, Arap, Wadih
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2010
נושאים:
Technical Advance
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3007161/
https://ncbi.nlm.nih.gov/pubmed/21183793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI44798
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים