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Factors important in evolutionary shaping of immunoglobulin gene loci

BACKGROUND: The extraordinary diversity characterizing the antibody repertoire is generated by both evolution and lymphocyte development. Much of this diversity is due to the existence of immunoglobulin (Ig) variable region gene segment libraries, which were diversified during evolution and, in high...

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Detalhes bibliográficos
Main Authors: Barak, Michal, Eilat, Guy, Unger, Ron, Mehr, Ramit
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006366/
https://ncbi.nlm.nih.gov/pubmed/21134249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1745-7580-6-13
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