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TGF-β-induced growth inhibition in B-cell lymphoma correlates with Smad1/5 signalling and constitutively active p38 MAPK

BACKGROUND: Cytokines of the transforming growth factor β (TGF-β) superfamily exert effects on proliferation, apoptosis and differentiation in various cell types. Cancer cells frequently acquire resistance to the anti-proliferative signals of TGF-β, which can be due to mutations in proteins of the s...

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Detalhes bibliográficos
Main Authors: Bakkebø, Maren, Huse, Kanutte, Hilden, Vera I, Smeland, Erlend B, Oksvold, Morten P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006362/
https://ncbi.nlm.nih.gov/pubmed/21092277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2172-11-57
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