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Stochastic Competition between Mechanistically Independent Slippage and Death Pathways Determines Cell Fate during Mitotic Arrest

Variability in cell-to-cell behavior within clonal populations can be attributed to the inherent stochasticity of biochemical reactions. Most single-cell studies have examined variation in behavior due to randomness in gene transcription. Here we investigate the mechanism of cell fate choice and the...

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Detalhes bibliográficos
Main Authors: Huang, Hsiao-Chun, Mitchison, Timothy J., Shi, Jue
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3006339/
https://ncbi.nlm.nih.gov/pubmed/21203573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015724
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