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Cell Death Response to Anti-mitotic Drug Treatment in Cell culture, Mouse Tumor Model and the Clinic

Anti-mitotic cancer drugs include classic microtubule-targeting drugs, such as taxanes and vinca alkaloids, and the newer spindle-targeting drugs, such as inhibitors of the motor protein, Kinesin-5 (aka KSP, Eg5, KIF11), and Aurora-A, Aurora-B and Polo-like kinases. Microtubule-targeting drugs are a...

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Detalhes bibliográficos
Publicado no:Endocr Relat Cancer
Main Authors: Shi, Jue, Mitchison, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557680/
https://ncbi.nlm.nih.gov/pubmed/28249963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-17-0003
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