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Ca(2+) clock malfunction in a canine model of pacing-induced heart failure
The mechanisms of sinoatrial node (SAN) dysfunction in heart failure (HF) remain unclear. We hypothesized that impaired rhythmic spontaneous sarcoplasmic reticulum Ca(2+) release (Ca(2+) clock) plays an important role in SAN dysfunction in HF. HF was induced in canine hearts by rapid ventricular pac...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Physiological Society
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3006277/ https://ncbi.nlm.nih.gov/pubmed/20889842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00723.2010 |
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