Mechanisms of sinoatrial node dysfunction in a canine model of pacing-induced atrial fibrillation

BACKGROUND: The mechanism of sinoatrial node (SAN) dysfunction in atrial fibrillation (AF) is unclear. OBJECTIVE: The purpose of this study was to test the hypothesis that defective spontaneous sarcoplasmic reticulum (SR) Ca(2+) release (Ca(2+) clock) is in part responsible for SAN dysfunction in AF...

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Bibliografiske detaljer
Main Authors: Joung, Boyoung, Lin, Shien-Fong, Chen, Zhenhui, Antoun, Patrick S., Maruyama, Mitsunori, Han, Seongwook, Piccirillo, Gianfranco, Stucky, Marcelle, Zipes, Douglas P., Chen, Peng-Sheng, Das, Mithilesh Kumar
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925681/
https://ncbi.nlm.nih.gov/pubmed/19914141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hrthm.2009.09.018
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