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TSCC: Two-Stage Combinatorial Clustering for virtual screening using protein-ligand interactions and physicochemical features

BACKGROUND: The increasing numbers of 3D compounds and protein complexes stored in databases contribute greatly to current advances in biotechnology, being employed in several pharmaceutical and industrial applications. However, screening and retrieving appropriate candidates as well as handling fal...

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Main Authors: Clinciu, Daniel L, Chen, Yen-Fu, Ko, Cheng-Neng, Lo, Chi-Chun, Yang, Jinn-Moon
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005922/
https://ncbi.nlm.nih.gov/pubmed/21143810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S4-S26
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