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TSCC: Two-Stage Combinatorial Clustering for virtual screening using protein-ligand interactions and physicochemical features

BACKGROUND: The increasing numbers of 3D compounds and protein complexes stored in databases contribute greatly to current advances in biotechnology, being employed in several pharmaceutical and industrial applications. However, screening and retrieving appropriate candidates as well as handling fal...

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Bibliographische Detailangaben
Hauptverfasser: Clinciu, Daniel L, Chen, Yen-Fu, Ko, Cheng-Neng, Lo, Chi-Chun, Yang, Jinn-Moon
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005922/
https://ncbi.nlm.nih.gov/pubmed/21143810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-11-S4-S26
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