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Meclizine is neuroprotective in models of Huntington's disease

Defects in cellular energy metabolism represent an early feature in a variety of human neurodegenerative diseases. Recent studies have shown that targeting energy metabolism can protect against neuronal cell death in such diseases. Here, we show that meclizine, a clinically used drug that we have re...

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Bibliografske podrobnosti
Main Authors: Gohil, Vishal M., Offner, Nicolas, Walker, James A., Sheth, Sunil A., Fossale, Elisa, Gusella, James F., MacDonald, Marcy E., Neri, Christian, Mootha, Vamsi K.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005902/
https://ncbi.nlm.nih.gov/pubmed/20977989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq464
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