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Genetic analysis of the GRIK2 modifier effect in Huntington's disease

BACKGROUND: In Huntington's disease (HD), age at neurological onset is inversely correlated with the length of the CAG trinucleotide repeat mutation, but can be modified by genetic factors beyond the HD gene. Association of a relatively infrequent 16 TAA allele of a trinucleotide repeat polymor...

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Bibliografische gegevens
Hoofdauteurs: Zeng, Wenqi, Gillis, Tammy, Hakky, Michael, Djoussé, Luc, Myers, Richard H, MacDonald, Marcy E, Gusella, James F
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2006
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618398/
https://ncbi.nlm.nih.gov/pubmed/16959037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-7-62
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