5-Androstenediol Ameliorates Pleurisy, Septic Shock, and Experimental Autoimmune Encephalomyelitis in Mice

Androstenediol (androst-5-ene-3β,17β-diol; 5-AED), a natural adrenal steroid, has been shown to suppress experimental autoimmune encephalomyelitis (EAE) in female SJL/J mice. We here report that 5-AED limits inflammation and proinflammatory cytokines including TNFα in murine models of carrageenan-in...

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Hauptverfasser: Nicoletti, Ferdinando, Auci, Dominick L., Mangano, Katia, Flores-Riveros, Jaime, Villegas, Sonia, Frincke, James M., Reading, Christopher L., Offner, Halina
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE-Hindawi Access to Research 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005896/
https://ncbi.nlm.nih.gov/pubmed/21188238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/757432
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