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The defect in CEACAM family member expression in Crohn’s disease IECs is regulated by the transcription factor SOX9

BACKGROUND: CEACAM1, CEACAM5 and CEACAM6 represent three of the CEACAM subfamily members expressed on intestinal epithelial cells (IECs). Deficiency in their expression, as seen in inflammatory bowel disease (IBD), results in the lack of activation of CD8+ regulatory T cells in the mucosa. Since CEA...

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מידע ביבליוגרפי
Main Authors: Roda, Giulia, Dahan, Stephanie, Mezzanotte, Laura, Caponi, Alessandra, Roth-Walter, Franziska, Pinn, David, Mayer, Lloyd
פורמט: Artigo
שפה:Inglês
יצא לאור: 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005567/
https://ncbi.nlm.nih.gov/pubmed/19637360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ibd.21023
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