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Suppression of Th1 and Th17, but not Th2, responses in a CD8(+) T cell mediated model of oral tolerance
The role of CD8(+) T cells in oral tolerance remains unclear. To address this, we developed a model to induce CD8(+) Tregs by feeding the MHC Class I immunodominant epitope of OVA, OVA((257–264)). OVA((257–264))-feeding induced tolerance similar to that observed in OVA protein-fed mice, capable of s...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857757/ https://ncbi.nlm.nih.gov/pubmed/19571798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2009.93 |
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