SOX9 indirectly regulates CEACAM1 expression and immune resistance in melanoma cells

As melanoma cells are immunogenic, they instigate an adaptive immune response and production of anti-tumor T-cells. A central factor in this interaction is CEACAM1 (carcinoembryonic antigen cell adhesion molecule 1), a transmembrane glycoprotein previously shown in our lab to protect melanoma cells...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Ashkenazi, Shira, Ortenberg, Rona, Besser, Michal, Schachter, Jacob, Markel, Gal
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
Subjects:
Research Paper: Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5058672/
https://ncbi.nlm.nih.gov/pubmed/26885752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7379
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