Preferential infection and depletion of Mycobacterium tuberculosis–specific CD4 T cells after HIV-1 infection

HIV-1 infection results in the progressive loss of CD4 T cells. In this study, we address how different pathogen-specific CD4 T cells are affected by HIV infection and the cellular parameters involved. We found striking differences in the depletion rates between CD4 T cells to two common opportunist...

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Main Authors: Geldmacher, Christof, Ngwenyama, Njabulo, Schuetz, Alexandra, Petrovas, Constantinos, Reither, Klaus, Heeregrave, Edwin J., Casazza, Joseph P., Ambrozak, David R., Louder, Mark, Ampofo, William, Pollakis, Georgios, Hill, Brenna, Sanga, Erica, Saathoff, Elmar, Maboko, Leonard, Roederer, Mario, Paxton, William A., Hoelscher, Michael, Koup, Richard A.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005236/
https://ncbi.nlm.nih.gov/pubmed/21115690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20100090
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