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Activation of NAD(P)H oxidases by Thromboxane A(2) Receptor Uncouples Endothelial Nitric Oxide Synthase

OBJECTIVE: The thromboxane receptor (TPr) and multiple TPr ligands, including thromboxane A(2) (TxA(2)) and prostaglandin H(2) (PGH(2)), are elevated during vascular and atherothrombotic diseases. How TPr stimulation causes vascular injury remains poorly defined. This study was conducted to investig...

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Main Authors: Zhang, Miao, Song, Ping, Xu, Jian, Zou, Ming-Hui
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005129/
https://ncbi.nlm.nih.gov/pubmed/20947827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.207712
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