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Activation of NAD(P)H oxidases by Thromboxane A(2) Receptor Uncouples Endothelial Nitric Oxide Synthase

OBJECTIVE: The thromboxane receptor (TPr) and multiple TPr ligands, including thromboxane A(2) (TxA(2)) and prostaglandin H(2) (PGH(2)), are elevated during vascular and atherothrombotic diseases. How TPr stimulation causes vascular injury remains poorly defined. This study was conducted to investig...

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Detalhes bibliográficos
Principais autores: Zhang, Miao, Song, Ping, Xu, Jian, Zou, Ming-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3005129/
https://ncbi.nlm.nih.gov/pubmed/20947827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.207712
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