Modifying the Substrate Specificity of Carcinoscorpius rotundicauda Serine Protease Inhibitor Domain 1 to Target Thrombin

Protease inhibitors play a decisive role in maintaining homeostasis and eliciting antimicrobial activities. Invertebrates like the horseshoe crab have developed unique modalities with serine protease inhibitors to detect and respond to microbial and host proteases. Two isoforms of an immunomodulator...

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Bibliografski detalji
Glavni autori: Giri, Pankaj Kumar, Tang, Xuhua, Thangamani, Saravanan, Shenoy, Rajesh T., Ding, Jeak Ling, Swaminathan, Kunchithapadam, Sivaraman, J.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004852/
https://ncbi.nlm.nih.gov/pubmed/21188150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015258
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