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NMR Structure of Carcinoscorpius rotundicauda Thioredoxin-related Protein 16 and Its Role in Regulating Transcription Factor NF-κB Activity

Thioredoxins (Trxs), which play a key role in maintaining a redox environment in the cell, are found in almost all organisms. Trxs act as potential reducing agents of disulfide bonds and contain two vicinal cysteines in a CXXC motif at the active site. Trx is also known to activate the DNA binding a...

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Dettagli Bibliografici
Autori principali: Giri, Pankaj Kumar, Jing-Song, Fan, Shanmugam, Muthu K., Ding, Jeak Ling, Sethi, Gautam, Swaminathan, Kunchithapadam, Sivaraman, J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436172/
https://ncbi.nlm.nih.gov/pubmed/22763700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.379859
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