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Consequences of Daily Administered Parathyroid Hormone on Myeloma Growth, Bone Disease, and Molecular Profiling of Whole Myelomatous Bone

BACKGROUND: Induction of osteolytic bone lesions in multiple myeloma is caused by an uncoupling of osteoclastic bone resorption and osteoblastic bone formation. Current management of myeloma bone disease is limited to the use of antiresorptive agents such as bisphosphonates. METHODOLOGY/PRINCIPAL FI...

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Autors principals: Pennisi, Angela, Ling, Wen, Li, Xin, Khan, Sharmin, Wang, Yuping, Barlogie, Bart, Shaughnessy, John D., Yaccoby, Shmuel
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004797/
https://ncbi.nlm.nih.gov/pubmed/21188144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015233
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