Llwytho...

A protein-based EM label for RNA identifies the location of exons in spliceosomes

To locate key RNA features in the structure of the spliceosome by EM, we fused a sequence-specific RNA binding protein to a protein with a distinct donut-shaped structure. We used this fusion to label spliceosomes assembled on a pre-mRNA that contained the target sequence in the exons. The label is...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Alcid, Eric A, Jurica, Melissa S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004785/
https://ncbi.nlm.nih.gov/pubmed/18223660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1378
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