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CCL22 regulates experimental autoimmune encephalomyelitis by controlling inflammatory macrophage accumulation and effector function

EAE is a demyelinating disease of the CNS and serves as a mouse model of MS. Expression of CCL22 in the draining LNs and spinal cord correlated with the onset of clinical EAE development and remained elevated. Administration of anti-CCL22 at the time of autoantigen immunization delayed the initiatio...

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Hlavní autoři: Dogan, Rukiye-Nazan E., Long, Nancy, Forde, Eileen, Dennis, Kristen, Kohm, Adam P., Miller, Stephen D., Karpus, William J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Leukocyte Biology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004518/
https://ncbi.nlm.nih.gov/pubmed/20940325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0810442
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