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Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance

Insulin resistance is a major factor in the pathogenesis of type 2 diabetes in the elderly. To investigate how insulin resistance arises, we studied healthy, lean, elderly and young participants matched for lean body mass and fat mass. Elderly study participants were markedly insulin-resistant as co...

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Autors principals: Petersen, Kitt Falk, Befroy, Douglas, Dufour, Sylvie, Dziura, James, Ariyan, Charlotte, Rothman, Douglas L., DiPietro, Loretta, Cline, Gary W., Shulman, Gerald I.
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004429/
https://ncbi.nlm.nih.gov/pubmed/12750520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1082889
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