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Mitochondrial Dysfunction in the Elderly: Possible Role in Insulin Resistance

Insulin resistance is a major factor in the pathogenesis of type 2 diabetes in the elderly. To investigate how insulin resistance arises, we studied healthy, lean, elderly and young participants matched for lean body mass and fat mass. Elderly study participants were markedly insulin-resistant as co...

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Detalhes bibliográficos
Main Authors: Petersen, Kitt Falk, Befroy, Douglas, Dufour, Sylvie, Dziura, James, Ariyan, Charlotte, Rothman, Douglas L., DiPietro, Loretta, Cline, Gary W., Shulman, Gerald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004429/
https://ncbi.nlm.nih.gov/pubmed/12750520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1082889
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