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p53: The Attractive Tumor Suppressor in the Cancer Research Field

p53 is one of the most studied tumor suppressors in the cancer research field. Of note, over 50% of human tumors carry loss of function mutations, and thus p53 has been considered to be a classical Knudson-type tumor suppressor. From the functional point of view, p53 is a nuclear transcription facto...

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Main Authors: Ozaki, Toshinori, Nakagawara, Akira
Formato: Artigo
Idioma:Inglês
Publicado: Hindawi Publishing Corporation 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004423/
https://ncbi.nlm.nih.gov/pubmed/21188172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/603925
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