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Effects of PON Polymorphisms and Haplotypes on Molecular Phenotype in Mexican-American Mothers and Children

Paraoxonase 1 (PON1) prevents oxidation of low density lipoproteins and inactivates toxic oxon derivatives of organophosphate pesticides (OPs). Over 250 SNPs have been previously identified in the PON1 gene, yet studies of PON1 genetic variation focus primarily on a few promoter SNPs (-108,-162) and...

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Bibliografiske detaljer
Main Authors: Huen, Karen, Barcellos, Lisa, Beckman, Kenneth, Rose, Sherri, Eskenazi, Brenda, Holland, Nina
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003760/
https://ncbi.nlm.nih.gov/pubmed/20839225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20567
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