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Developmental Changes in PON1 Enzyme Activity in Young Children and Effects of PON1 Polymorphisms

BACKGROUND: Paraoxonase 1 (PON1) is an enzyme that detoxifies activated organophosphorus pesticides (OPs) and is also involved in oxidative stress pathways. OBJECTIVES: PON1 activity in newborns is lower than in adults, but the ontogeny of PON1 activity is poorly characterized in young children. We...

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Detalhes bibliográficos
Main Authors: Huen, Karen, Harley, Kim, Brooks, Jordan, Hubbard, Alan, Bradman, Asa, Eskenazi, Brenda, Holland, Nina
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2790521/
https://ncbi.nlm.nih.gov/pubmed/20019917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.0900870
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