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PON1 and Neurodevelopment in Children from the CHAMACOS Study Exposed to Organophosphate Pesticides in Utero

BACKGROUND: Paraoxonase 1 (PON1) detoxifies oxon derivatives of some organophosphate (OP) pesticides, and its genetic polymorphisms influence enzyme activity and quantity. We previously reported that maternal urinary concentrations of dialkyl phosphate (DAP) metabolites, a marker of OP pesticide exp...

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Главные авторы: Eskenazi, Brenda, Huen, Karen, Marks, Amy, Harley, Kim G., Bradman, Asa, Barr, Dana Boyd, Holland, Nina
Формат: Artigo
Язык:Inglês
Опубликовано: National Institute of Environmental Health Sciences 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002199/
https://ncbi.nlm.nih.gov/pubmed/21126941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1002234
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