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Effects of PON Polymorphisms and Haplotypes on Molecular Phenotype in Mexican-American Mothers and Children

Paraoxonase 1 (PON1) prevents oxidation of low density lipoproteins and inactivates toxic oxon derivatives of organophosphate pesticides (OPs). Over 250 SNPs have been previously identified in the PON1 gene, yet studies of PON1 genetic variation focus primarily on a few promoter SNPs (-108,-162) and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huen, Karen, Barcellos, Lisa, Beckman, Kenneth, Rose, Sherri, Eskenazi, Brenda, Holland, Nina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003760/
https://ncbi.nlm.nih.gov/pubmed/20839225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.20567
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