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Mutational analysis of kinetic partitioning in protein folding and protein–DNA binding
Kinetic partitioning between competing routes is present in many biological processes. Here, we propose a methodology to characterize kinetic partitioning through site-directed mutagenesis and apply it to parallel routes for unfolding of the TI I27 protein and for recognition of its target DNA by th...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003449/ https://ncbi.nlm.nih.gov/pubmed/20876193 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/protein/gzq064 |
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