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Detection of DNA Strand Breaks in Apoptotic Cells by Flow- and Image-Cytometry
Extensive DNA fragmentation that generates a multitude of DNA double-strand breaks (DSBs) is a hallmark of apoptosis. A widely used approach to identify apoptotic cells relies on labeling DSBs in situ with fluorochromes. Flow or image cytometry is then used to detect and quantify apoptotic cells lab...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003436/ https://ncbi.nlm.nih.gov/pubmed/21057923 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-60327-409-8_8 |
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