A Single Amino Acid in Human APOBEC3F Alters Susceptibility to HIV-1 Vif

Human APOBEC3F (huA3F) potently restricts the infectivity of HIV-1 in the absence of the viral accessory protein virion infectivity factor (Vif). Vif functions to preserve viral infectivity by triggering the degradation of huA3F but not rhesus macaque A3F (rhA3F). Here, we use a combination of delet...

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Bibliografske podrobnosti
Main Authors: Albin, John S., LaRue, Rebecca S., Weaver, Jessalyn A., Brown, William L., Shindo, Keisuke, Harjes, Elena, Matsuo, Hiroshi, Harris, Reuben S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Microbiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003379/
https://ncbi.nlm.nih.gov/pubmed/20971849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173161
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