A Single Amino Acid in Human APOBEC3F Alters Susceptibility to HIV-1 Vif

Human APOBEC3F (huA3F) potently restricts the infectivity of HIV-1 in the absence of the viral accessory protein virion infectivity factor (Vif). Vif functions to preserve viral infectivity by triggering the degradation of huA3F but not rhesus macaque A3F (rhA3F). Here, we use a combination of delet...

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Bibliographische Detailangaben
Hauptverfasser: Albin, John S., LaRue, Rebecca S., Weaver, Jessalyn A., Brown, William L., Shindo, Keisuke, Harjes, Elena, Matsuo, Hiroshi, Harris, Reuben S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Microbiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003379/
https://ncbi.nlm.nih.gov/pubmed/20971849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.173161
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