A carregar...
State-dependent Regulation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gating by a High Affinity Fe(3+) Bridge between the Regulatory Domain and Cytoplasmic Loop 3
The unique regulatory (R) domain differentiates the human CFTR channel from other ATP-binding cassette transporters and exerts multiple effects on channel function. However, the underlying mechanisms are unclear. Here, an intracellular high affinity (2.3 × 10(−19) m) Fe(3+) bridge is reported as a n...
Na minha lista:
| Autor principal: | |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003342/ https://ncbi.nlm.nih.gov/pubmed/20952391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.161497 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|