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Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons

BACKGROUND: Oxaliplatin chemotherapy induced neuropathy is a dose related cumulative toxicity that manifests as tingling, numbness, and chronic pain, compromising the quality of life and leading to discontinued chemotherapy. Patients report marked hypersensitivity to cold stimuli at early stages of...

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Detalhes bibliográficos
Main Authors: Anand, Uma, Otto, William R, Anand, Praveen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003244/
https://ncbi.nlm.nih.gov/pubmed/21106058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-82
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