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Neurokinin 2 receptor-mediated activation of protein kinase C modulates capsaicin responses in DRG neurons from adult rats

Patch-clamp techniques and Ca(2+) imaging were used to examine the interaction between neurokinins (NK) and the capsaicin (CAPS)-evoked transient receptor potential vanilloid receptor 1 (TRPV1) responses in rat dorsal root ganglia neurons. Substance P (SP; 0.2–0.5 μm) prevented the reduction of Ca(2...

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Detalhes bibliográficos
Main Authors: Sculptoreanu, Adrian, Kullmann, F. Aura, de Groat, William C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896238/
https://ncbi.nlm.nih.gov/pubmed/18598261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06267.x
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