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Sensitization of capsaicin and icilin responses in oxaliplatin treated adult rat DRG neurons

BACKGROUND: Oxaliplatin chemotherapy induced neuropathy is a dose related cumulative toxicity that manifests as tingling, numbness, and chronic pain, compromising the quality of life and leading to discontinued chemotherapy. Patients report marked hypersensitivity to cold stimuli at early stages of...

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Autors principals: Anand, Uma, Otto, William R, Anand, Praveen
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003244/
https://ncbi.nlm.nih.gov/pubmed/21106058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-82
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