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Distinct Functions for the Drosophila piRNA Pathway in Genome Maintenance and Telomere Protection

Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway has additional functions during development. Here...

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Autors principals: Khurana, Jaspreet S., Xu, Jia, Weng, Zhiping, Theurkauf, William E.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003142/
https://ncbi.nlm.nih.gov/pubmed/21179579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001246
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