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Distinct Functions for the Drosophila piRNA Pathway in Genome Maintenance and Telomere Protection

Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway has additional functions during development. Here...

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Hlavní autoři: Khurana, Jaspreet S., Xu, Jia, Weng, Zhiping, Theurkauf, William E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003142/
https://ncbi.nlm.nih.gov/pubmed/21179579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001246
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