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Distinct Functions for the Drosophila piRNA Pathway in Genome Maintenance and Telomere Protection

Transposons and other selfish DNA elements can be found in all phyla, and mobilization of these elements can compromise genome integrity. The piRNA (PIWI-interacting RNA) pathway silences transposons in the germline, but it is unclear if this pathway has additional functions during development. Here...

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Detalhes bibliográficos
Main Authors: Khurana, Jaspreet S., Xu, Jia, Weng, Zhiping, Theurkauf, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003142/
https://ncbi.nlm.nih.gov/pubmed/21179579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001246
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