Wird geladen...

Effects of pH on aggregation kinetics of the repeat domain of a functional amyloid, Pmel17

Pmel17 is a functional amyloidogenic protein whose fibrils act as scaffolds for pigment deposition in human skin and eyes. We have used the repeat domain (RPT, residues 315–444), an essential luminal polypeptide region of Pmel17, as a model system to study conformational changes from soluble unstruc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Pfefferkorn, Candace M., McGlinchey, Ryan P., Lee, Jennifer C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003087/
https://ncbi.nlm.nih.gov/pubmed/21106765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006424107
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!