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Localization of uPAR and MMP-9 in lipid rafts is critical for migration, invasion and angiogenesis in human breast cancer cells

BACKGROUND: uPAR and MMP-9, which play critical roles in tumor cell invasion, migration and angiogenesis, have been shown to be associated with lipid rafts. METHODS: To investigate whether cholesterol could regulate uPAR and MMP-9 in breast carcinoma, we used MβCD (methyl beta cyclodextrin, which ex...

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Detalhes bibliográficos
Main Authors: Raghu, Hari, Sodadasu, Prasanna Kumar, Malla, Rama Rao, Gondi, Christopher S, Estes, Norman, Rao, Jasti S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002355/
https://ncbi.nlm.nih.gov/pubmed/21106094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-647
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