Mechanical ventilation modulates Toll-like receptor-3-induced lung inflammation via a MyD88-dependent, TLR4-independent pathway: a controlled animal study

BACKGROUND: Mechanical ventilation augments lung inflammation resulting from exposure to microbial products. The objective of this study was to test the hypothesis that ventilator-associated immune modulation requires MyD88-dependent signaling. Because MyD88 is a critical adapter protein utilized fo...

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Autors principals: Chun, Carrie D, Liles, W Conrad, Frevert, Charles W, Glenny, Robb W, Altemeier, William A
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002319/
https://ncbi.nlm.nih.gov/pubmed/21092115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2466-10-57
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