Histone Deacetylase Inhibitors Downregulate Checkpoint Kinase 1 Expression to Induce Cell Death in Non-Small Cell Lung Cancer Cells

BACKGROUND: Histone deacetylase inhibitors (HDACis) are promising anticancer drugs; however, the molecular mechanisms leading to HDACi-induced cell death have not been well understood and no clear mechanism of resistance has been elucidated to explain limited efficacy of HDACis in clinical trials. M...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Brazelle, William, Kreahling, Jenny M., Gemmer, Jennifer, Ma, Yihong, Cress, W. Douglas, Haura, Eric, Altiok, Soner
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2010
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001870/
https://ncbi.nlm.nih.gov/pubmed/21179472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014335
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים