Histone deacetylase inhibitors promote glioma cell death by G2 checkpoint abrogation leading to mitotic catastrophe

Glioblastoma multiforme is resistant to conventional anti-tumoral treatments due to its infiltrative nature and capability of relapse; therefore, research efforts focus on characterizing gliomagenesis and identifying molecular targets useful on therapy. New therapeutic strategies are being tested in...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Cornago, M, Garcia-Alberich, C, Blasco-Angulo, N, Vall-llaura, N, Nager, M, Herreros, J, Comella, J X, Sanchis, D, Llovera, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237242/
https://ncbi.nlm.nih.gov/pubmed/25275596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.412
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