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Stress-regulated targeting of the NKG2D ligand Mult1 by a MARCH family E3 ligase

NKG2D is a stimulatory receptor expressed by NK cells and some T cell subsets. Expression of the self-encoded ligands for NKG2D is presumably tightly regulated to prevent autoimmune disorders while allowing detection of infected cells and developing tumors. The NKG2D ligand Mult1 is regulated at mul...

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Autors principals: Nice, Timothy J., Deng, Weiwen, Coscoy, Laurent, Raulet, David H.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001296/
https://ncbi.nlm.nih.gov/pubmed/20870941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000247
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